Election Results

APS thanks everyone who voted in the APS annual election. The results are in, and the newly elected board members and nominating committee are as follows:

Secretary
Mark P. Jensen, PhD

Directors

Nominating Committee - Past Presidents

Nominating Committee - Members-at-Large

Theodore Price, PhD	Steven Z. George, PT PhD
Ricardo A. Cruciani, MD PhD	Renee C. B. Manworren, MS RN BC CNS

Thanks also to everyone who ran in the election. Your willingness to lend your time and expertise to APS is truly valued. An additional thank you is due to the outgoing board members, whose dedication was apparent throughout their terms. APS has a great year ahead with many important initiatives on the agenda and an excellent team of volunteers to guide the way.

APS Annual Meeting
Register online today!
May 8-10, 2008
Tampa, FL

Annual Meeting Hotel Housing Information
Hotel reservations can be made online, by fax, or by mail using the APS housing form.

Reservation requests must be sent directly to the APS Housing Bureau through May 1, 2008. Do not send housing forms to APS headquarters or to individual conference hotels; this will delay the processing of your request.

A credit card guarantee of one night's room and tax is required with each reservation request. Housing forms received without a valid credit card will be returned and will not be processed. Credit cards must be valid through May 2008 to be considered a proper guarantee. No cash or check deposits will be accepted.

Continue to make, modify, or cancel reservations through May 1, 2008, via the APS Housing Bureau by Internet, fax, mail, or e-mail (Housing@visittampabay.com). After this date, direct all changes to the designated hotel. After April 4, 2008, and up to 72 hours before arrival, cancellations will be charged a $25 processing fee. Any cancellations within 72 hours of arrival are subject to one night's room and tax penalty.

APS Data Blitz for Clinical and Basic Science Research

APS is pleased to announce that the following abstracts will be presented during the Data Blitz on Wednesday, May 7, at 7pm, at the Tampa Convention Center:

A Comparison of Quantitative Analysis of Sleep Disturbance in Patients with Chronic Pain Versus Patients Without Chronic Pain
Robert Corba, DO; Maryjane Cerrone, MSN, RN,C; Jeffrey Gould, MD; Bruce Nicholson, MD; Robert Wertz, MD; Robert Wilson, DO; Mary Ann Yackabonis, RN; Denise Schuler; Lehigh Valley Hospital, Neurosciences and Pain Research.

Nociception and the Immune System in Infant Rats
Deirtra Hunter, PhD; Gordon Barr, PhD; New York Psychiatric Institute at Columbia Medical Center

Variations in Patient Controlled Analgesia Morphine Dosing Schedules During Acute Painful Episodes in Children with Sickle Cell Disease
Eufemia Jacob, PhD; Marilyn Hockenberry, PhD RN-CS PNP FAAN; Brigitta Mueller, MD MHCM; Thomas Coates, MD; Lonnie Zeltzer, MD; Texas Children's Hospital/Baylor College of Medicine

Functional MR Imaging of Amygdala and Insula Activation Associated with Affective Experience of Pain is Modified by Group CBT
G. Michael Krauthamer, MA; Julie Dumas, PhD; Paul Newhouse, MD; Frank Keefe, PhD; Magdalena Naylor, MD PhD; University of Vermont

The SPARC-KO Mouse as a Clinically-Relevant Behavioral Model of Low Back Pain Due to Degenerative Disc Disease
Magali Millecamps, PhD; Laura Stone; Helen Sage; McGill University, Faculty of Dentistry

Phenotypic Differences Between Genetically and Pharmacologically Lesioning the TRPV1 Receptor
John Neubert, DDS PhD; Heather L. Rossi, BA; Wendi Malphurs, BA; James P. Weaver, BA; Alan C. Jenkins, MS; Robert M. Caudle, PhD; University of Florida

Involvement of Ion Channels in Ischemic Pain Transduction
Rajan Radhakrishnan, PhD; Alan R. Light, PhD; Ron W. Hughen, BS; College of Pharmacy, University of Southern Nevada, South Jordan, UT and Department of Anesthesiology, University of Utah Medical School

Novel p-38 Inhibitor ARRY-371797 Provides Significant Analgesic Benefit Following Third Molar Extraction
Ann Remmers, PhD; John Yates, MD; Stephen Daniels, DO; Cynthia Martinez, RN; Array BioPharma, Inc.

Targeted Disruption of PSD-93 Gene Impairs Synaptic NMDA Receptor Function and Blunts Chronic Pain Via Alteration of NMDA Receptor Trafficking
Yuan-Xiang Tao, MD PhD; Gavin Rumbaugh; Min Zhuo; Xuguang Zhu; Roger A. Johns; Richard L. Huganir; David S. Bredt; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine

Treatment-Related Determinants of Return to Work Vary as a Function of Initial Levels of Pain Catastrophizing
Timothy Wideman, PT; Heather Adams, MSW; Michael JL Sullivan, PhD; McGill University

Highlights from The Journal of Pain

The following highlights summarize selected articles from the April 2008 issue (Volume 9, Number 4).

Spanish researchers evaluated 117 patients who had pain every day for at least 6 months. The mean age was 54, and 70% of participants were women. Each participant was interviewed by a psychologist.

The study concluded that patients who receive higher levels of social support not only show lower incidence of depression, but also have less pain. The authors noted that reduced pain intensity decreases impairment and increases the ability to function. The study underscores the potential importance of psychosocial factors in helping patients adjust to chronic pain.

Catastrophizing and Pain-Coping in Young Adults: Associations With Depressive Symptoms and Headache Pain
Luis F. Buenaver, Robert R. Edwards, Michael T. Smith, Sandra E. Gramling, and Jennifer A. Haythornthwaite, Johns Hopkins University School of Medicine, Baltimore, MD

Catastrophizing—anxiety and magnified fear about pain—can exacerbate the pain experience. A study published in The Journal of Pain reports people who experience headaches demonstrate the highest levels of pain catastrophizing and have greater pain intensity and significant depressive symptoms.

Researchers from Johns Hopkins University evaluated 202 undergraduate students in two groups: those with problem headaches and pain-free subjects. They were evaluated with the Headache and Facial Pain Screening Questionnaire, the Beck Depression Inventory, and the Coping Strategies Questionnaire.

The researchers found no significant differences in catastrophizing between the problem headache group and the pain-free subjects. However, the headache group reported greater depressive symptoms. Further, although higher levels of catastrophizing predicted more severe headache pain and depressive symptoms, the use of other coping strategies did not influence pain or depression. The authors concluded their findings reflect the major role catastrophizing and other negative emotional responses play in shaping pain-related outcomes.

Effect of Concomitant Ingestion of Alcohol on the In Vivo Pharmacokinetics of Kadian (Morphine Sulfate Extended-Release) Capsules
Franklin Johnson, George Wagner, Stephen Sun, and Joseph Stauffer, Alpharma Pharmaceuticals, Piscataway, NJ

A study published in The Journal of Pain shows an extended-release form of morphine, Kadian, has negligible risk for harmful interaction with alcohol.

Alcohol enhances the effects of opioids on the central nervous system, and even moderate drinking poses potential drug interactions. Combining alcohol and pharmaceuticals, according to the Drug Abuse Warning Network, accounted for 13.5% of all emergency department visits in 2005.

Following the withdrawal of Palladone from the market, the FDA advised makers of other extended-release opioids to determine the risk of alcohol-induced dose dumping, in which an unintended rapid release of the active drug occurs. Opioid-naive healthy adult men with a history of moderate alcohol consumption were evaluated. Subjects were randomly assigned to three interactions of Kadian when dosed with alcohol in fasting and fed subjects: Kadian with four shots of 80-proof alcohol and water while fasting, Kadian with four shots of alcohol after ingesting a high-fat meal, and Kadian with water while fasting.

The authors observed no drug interactions with alcohol, indicating the extended-release mode of action was not significantly affected by alcohol. They noted it is not known why some extended-release opioid formulations are subject to dose dumping with alcohol and others are not. Nevertheless, patients should be advised to avoid alcohol when taking opioid medications.

Highlights from Pain Medicine

The following highlights summarize selected articles from the January/February 2008 issue (Volume 9, Number 1).

Pain Experience of Children with Sickle Cell Disease Who Had Prolonged Hospitalizations for Acute Pain Episodes
Eufemia Jacob* and Brigitta U. Mueller†*
Texas Children's Center and †Texas Children's Sickle Cell Center, Baylor College of Medicine, Department of Pediatrics, Clinical Care Center, Houston, TX

For patients with sickle cell disease (SCD), vaso-occlusive episodes account for 79%-91% of their emergency department visits and 59%-68% of their hospitalizations. With growing recognition that acute painful experiences can lead to long-term consequences, this study examined pain management in children who had prolonged hospital stays of more than 10 days for acute painful episodes.

Researchers reviewed patients' medical records for pain intensity ratings, patterns of analgesic use and patient-controlled analgesia (PCA) regimens, and differences in pain intensity and pain management between short (fewer than 10 days) and prolonged hospital stays for acute painful episodes. They found these children reported high pain intensity rates throughout their hospitalizations. The medications used most frequently were morphine delivered via PCA, long-acting morphine, and ketorolac. Significantly higher amounts of morphine were used during hospital stays lasting longer than 10 days; however, the researchers stressed "the maximum administered amount was on the average only 37% of the prescribed amount of any given day."

High-to-moderate levels of pain intensity ratings were persistently reported. The researchers suggest future research should focus on pain management regimens "that would lead to optimal relief and minimize the negative consequences associated with painful episodes in children with SCD."

Two-Minute Skin Anesthesia Through Ultrasound Pretreatment and Iontophoretic Delivery of a Topical Anesthetic: A Feasibility Study
Egilius L.H. Spierings,* Julie A. Brevard,† and Nathaniel P. Katz†
*MedVadis Research Corp., Wellesley Hills, MA; †Inflexxion Inc., Newton, MA

"Ultrasound pretreatment plus 2-minute low-voltage iontophoresis provides better skin anesthesia than sham-ultrasound plus 2-minute low-voltage iontophoresis, and standard, 10-minute high-voltage iontophoresis."

This was the conclusion of a single-blind randomized study of healthy volunteers who were subjected to a standardized needle prick. They rated absolute pain on a 10-cm visual-analog scale.

The mean duration of the ultrasound pretreatment was 21.4 seconds for the study's 30 participants. Although the absolute pain scores for the ultrasound plus 2-minute low-voltage iontophoresis and the standard, 10-minute high-voltage iontophoresis were not statistically significantly different, they were significantly different from the sham-ultrasound plus 2-minute low-voltage iontophoresis pain score.

"Ultrasound shortens the duration and intensity of the iontophoresis required to anesthetize the skin, providing anesthesia to needle prick in 2 minutes," the researchers stated. "Ultrasound and iontophoresis are technologies currently available for use in clinical practice, but the development of a single device, combining the two, would probably facilitate and encourage their combined use, pending further studies confirming benefit in practice."

APS to Present First Pain Disparities Award

In March, the APS Executive Committee approved a Pain Disparities Award to be presented by the Advisory Board of the Pain and Disparities Special Interest Group (SIG). The award was established to highlight significant research contributions in the area of pain management disparities and to encourage future research related to eliminating disparities in pain management. The first Pain Disparities Award will be conferred at the 2008 Annual Meeting of the Pain and Disparities SIG and will recognize the scientific poster with the strongest implications for reducing disparities in pain management. The complete award proposal, including the review process and criteria, can be accessed by visiting the Pain and Disparities SIG Web site at www.ampainsoc.org/member/sigsites/disparity.

APS Honors Multidisciplinary Pain Care

To further showcase its 30 years of leadership in pain management, APS has initiated a Clinical Centers of Excellence (CCOE) in Pain Management Awards Program to recognize top-quality clinical care in pain management. Now in its second year, the program continues to gain momentum.

Many people contributed their time and talents to this ambitious effort. APS wishes to thank this year's CCOE committee—Chair Michael E. Clark and committee members Judy Paice, Elsayed Abdel-Moty, Christopher Gharibo, Kenneth Goldschneider, Robert Jamison, Mark Jensen, Dennis Turk, and Christine Zampach—as well as the APS staff and Endo Pharmaceuticals Inc.; Abbott Laboratories; Alpharma Pharmaceuticals, LLC; Cephalon, Inc.; Eli Lilly & Company; King Pharmaceuticals; Purdue Pharma; and Wyeth Pharmaceuticals for their financial support of the 2008 program.

APS is proud to recognize the 2008 CCOE award recipients:

• UW Health, University of Wisconsin-Madison Pain Care Services, Madison, WI
• Pediatric Pain Management Center at Oregon Health & Science University/Doernbecher Children's Hospital, Portland, OR
• PRIDE: Productive Rehabilitation Institute of Dallas for Ergonomics, Dallas, TX
• Division of Pain Management, Stanford University, Palo Alto, CA
• Fairview Pain and Palliative Care Center, University of Minnesota Medical Center, Minneapolis, MN
• Richard Barrett Pain Management Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH

These programs represent the many clinical programs throughout the United States that overcome challenges to provide exemplary multidisciplinary pain care to patients.

APS also recognizes the following programs as 2008 CCOE Honorable Mentions:

• Whole Child and Family Pediatric Pain, UCLA Pediatric Pain Program
• Pain Medicine at the University of Texas M. D. Anderson Cancer Center
• Bay Area Pain & Wellness Center
• Massachusetts General Hospital Center for Pain Medicine
• Adolf Meyer Chronic Pain Treatment Program at Johns Hopkins
• Department of Pain Medicine and Palliative Care, Beth Israel Medical Center
• Minnesota Head and Neck Pain Clinic, University of Minnesota
• University of California, San Diego Center for Pain Medicine
• Jane B. Pettit Pain and Palliative Care Center, Children's Hospital of Wisconsin/Medical College of Wisconsin

Show Your Support:
CCOE and APS Awards Gala
Westin Tampa Harbour Island, Tampa, FL

APS believes a special award deserves a special celebration. To honor the 2008 CCOE award recipients, APS will host a gala on Thursday, May 8, 2008, at its Annual Scientific Meeting in Tampa. The program has been expanded to include the annual APS awards, so this event will truly be a celebration for all!

Award recipients and hundreds of guests will enjoy cocktails and dinner at the Harbour Island Ballroom of the Westin Tampa Harbour Island Hotel. The evening's presentation will include remarks from APS leadership, an award presentation, and acknowledgement of industry partners who have supported this magnificent program. The evening will commence at 7:30 pm and conclude at 10:30 pm.

Please show your support and commitment to multidisciplinary pain care by attending this prestigious event. Tickets may be purchased online for $75 per person at www.ampainsoc.org/meeting/annual_08/awards.htm.

For more information about the CCOE Program, please visit www.ampainsoc.org/awards.

Young Investigator Travel Award Recipients

APS is pleased to award Young Investigator Travel Awards to 47 trainees to help them attend the 2008 annual meeting. These individuals will present their research during designated paper and poster sessions. The APS meeting creates a milieu in which scientists and clinicians can share relevant information from their different perspectives; such exchanges frequently lead to advances in clinical care.

2008 Young Investigators
Ratan Banik, MBBS PhD, New Jersey Neuroscience Institute
Meredith Barad, MD, Stanford University
Emily Bartley, MS, University of Tulsa
Nancy Beckman, Rosalind Franklin University Medical School
Christopher Black, PhD, University of Georgia
Claudia Campbell, PhD, Johns Hopkins University
Mary Chandler, University of Tulsa
Ling-Chun Chiang, RN MSN, Case Western Reserve University
Sungkun Cho, University of Hawaii
Jody Coppersmith, Wayne State University
Jason Craggs, PhD, University of Florida
Kathleen Darchuk, PhD, Mayo Clinic
Margarete Dasilva, PhD DDS MS, University of Florida
Josimari DeSantana, PhD PT, University of Iowa
Toni Glover, MA RN, University of Florida
Burel Goodin, MA, University of Maryland Baltimore County
Gagandeep Goyal, MD, Hahnmann University Hospital
Morten Hadsel, DDS MS, Wake Forest University Baptist Medical Center
Linda Hatfield, PhD CNNP, Milton S. Hershey Medical Center
Adam Hirsh, University of Florida
Susan Hofkamp, PhD, Johns Hopkins University
Christopher King, PhD, University of Florida
Amy Lewandowski, MA, Case Western Reserve University-Portland
Amy Loree, Wayne State University
Yumi Maeda, DDS PhD, University of Iowa
Uta Maeda, Stanford University
Shail Maingi, MD, Memorial Sloan-Kettering Cancer Center
Michael McLoughlin, University of Wisconsin
Hannah Mercer, University of New England
Lisa Miller, Wayne State University
Satyanarayana Padi, PhD, Ghal Kalan
Sara Parke, Stanford University
Jeff Pasley, PhD, University of Georgia
Yunhai Qiu, MD PhD, University of Michigan
Alexandre Quevedo, PhD, Wake Forest University School of Medicine
Bridgett Rahim-Williams, PhD MA MPH, University of Florida
Patricia Robichaud, Université de Sherbrooke
Jennifer Russell, MA, University of Tulsa
Lauren Stutts, MS, University of Florida
Yannick Tousignant-Laflamme, PhD(c), Université de Sherbrooke
Joseph Wallach, PhD
Jen Wang, Stanford University
Charlie Wang, Stanford University
Whitney Worzer, MS CRC, University of Texas at Arlington
Jing Wu, MD PhD, Texas Tech University
Hong Yang, MD PhD, University of Texas Medical Branch
Jennifer Zinke, PhD, Northwestern University

New NIH Funding Opportunity: Genome-Wide Association Analysis of Existing Data Sets for Arthritis and Musculoskeletal and Skin Diseases

This Funding Opportunity Announcement (FOA) issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), solicits applications proposing genome-wide association studies (GWAS) of human phenotypes relevant to the NIAMS mission to be conducted with existing genetic and phenotypic data, such as may be obtained from the NIH database of Genotype and Phenotype (dbGaP) or other sources of genotype and phenotype data.

This FOA will advance understanding of arthritis and musculoskeletal and skin diseases. Such studies will not require genotyping of samples or recruitment or clinical characterization of subjects, and may be completed at modest cost and within 2 years. Awards under this FOA will provide support for personnel, data storage and computation, travel, and other costs as justified by the analysis design. For more information, visit http://grants.nih.gov/grants/ guide/pa-files/PAR-08-123.html.

Call for Applications

IASP is now accepting applications for the following research grants. Please note that the submission deadline for each of these grants is April 30, 2008.

For more details, including complete guidelines and requirements for these and other opportunities, please visit the IASP Grants page at www.iasp-pain.org/grants

2008 IASP Collaborative Research Grant
Award up to U.S. $15,000
Application Deadline: April 30, 2008

Purpose
This grant supports international, interdisciplinary collaborations in pain research.

Eligibility
The principal investigator in charge of the overall project must be an IASP member for at least 1 year before applying for this grant.

2008 IASP Research Grant Funded by the Scan | Design by Inger & Jens Bruun Foundation
Award: Up to U.S. $25,000
Application Deadline: April 30, 2008

Purpose
This grant aims to encourage and support collaborative, multidisciplinary research between two or more research groups located in the five Scandinavian countries (Denmark, Finland, Iceland, Norway, and Sweden) and the United States.

Eligibility
Investigators must be based in a Scandinavian country and the United States. The investigator in charge of the overall project must be an IASP member for at least 1 year before applying for this grant.

Call for 2008 Applications:
Mayday Pain & Society Fellowship

The Mayday Fund, a New York City foundation dedicated to alleviating the incidence, degree, and consequence of human physical pain, is accepting applications for the 2008 Mayday Pain & Society Fellowship: A Media & Policy Fellows Initiative. The program is designed to equip physicians, nurses, pharmacists, social workers, scientists, and legal scholars with the necessary skills to become effective advocates and spokespeople about pain issues in the United States and Canada. The six selected fellows will attend training in Washington, D.C., October 20-23, 2008, and have 5 months of coaching with a communications officer to track progress on their plans. Candidates for the fellowship must be accomplished experts in pain management, established at an institution with peer-reviewed research, and able and willing to devote a significant amount of time to using the skills learned in the Fellowship. Interested applicants may apply online at www.maydayfellows.org.

Annual Meeting Paper and Poster Abstracts Available Online

The abstracts to be presented as papers and posters during the annual meeting are now available in an online searchable database. The more than 340 abstracts represent the best innovations and research in the study and treatment of pain. Plan your poster viewing experience before the annual meeting by reviewing the abstract titles, author listings, and text online before your arrival in Tampa. Abstracts can be searched according to poster number, author, title, or keyword.
Click here to access the abstract database.

To register for the annual meeting, visit ampainsoc.org/meeting.

Update Your Contact Information

The APS Online Membership Directory is available year-round to keep you connected to your colleagues. To ensure your listing is accurate, log on to the Members Only section of the APS Web site.
Enter your Web ID (for first-time visitors, this is your Member ID) and password and click "Update Your Own Member Record."

If you need assistance, please contact APS Member Services at 847/375-4715.
Please note: APS does not sell or distribute your personal information.