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Library

APS Bulletin • Volume 15, Number 3, Summer 2005

Web Site Reviews

Michael E. Clark, PhD, Department Editor

Mouse Phenome Database

Reviewed by William R. Lariviere, PhD

http://www.jax.org/phenome

Site Audience

This Web site serves as a database for physiological, anatomical, and behavioral mouse strain data generated by the scientific community (similar to www.webqtl.org) and focuses on a set of 40 inbred strains for both sexes. Genotypic data have been collected as well. More than 25 pain traits and pain-related traits are part of this database. The Jackson Laboratory hosts the site, and private and public sources fund it.

Content Appraisal

Tools available allow users to view the trait data to examine strain means for their strain of interest, find outlier strains, and compare measurements for several strains through a variety of plots and text displays. Users can also calculate genetic correlations between traits and view scatter plots; submit newly generated strain data for inclusion with an evaluation process; and view and download single nuleotide polymorphism (SNP) data. Tools for comparison of SNP data with traits are not yet available. There is a Links page to related resources.

Navigation/Ease of Use

Navigation is easy—simply click on the menu bar, which is always present. The long list of phenotypes is grouped into categories or projects, making it easy to peruse.

Recommendations

This Web site and its features can be used for hypothesis generation and examining correlated traits for which common genetic mechanisms may exist. It lists more pain traits than WebQTL (www.webqtl.org) but has fewer analysis features.

William R. Lariviere, PhD, is Assistant Professor at University of Pittsburgh Medical Center, Pittsburg, PA.

Please direct your comments or suggestions for future Web Site Reviews to Michael E. Clark, PhD, Department Editor, at michaeleclark2@msn.com

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