| Table 1. Multiple Response Conceptualization of Clinical Pain |
| Response Category |
Examples |
| Neurophysiological |
| Ascending |
Afferent A-delta and C nerve excitation |
| Supraspinal/Cortical |
Hypothalamic, limbic, somatosensory excitation |
| Descending |
Efferent autonomic, pyramidal, extrapyramidal nerve excitation |
| Chemical |
Release of B-endorphin and enkephalin neuropeptides |
|
| Cognitive/subjective |
| Thoughts |
The pain is horrible, unbearable, out of control |
| Feelings states |
Perceptions of pain, fear/anxiety, anger, sadness/depression |
| Images |
Visualizations of being crippled, having surgery, losing a job |
|
| Gross motor |
| Verbal |
Moaning, crying/yelling, pain complaints |
| Nonverbal |
Guarding, squeezing, limping, lying down, taking analgesics |
|
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